:root{--nav:#112b32;--nav-muted:#a7bdc2;--ink:#172c35;--muted:#5c7079;--accent:#087d78;--accent-dark:#07625e;--canvas:#f3f6f8;--border:#dbe4e8;--white:#fff;--negative:#2166ac;--positive:#b2182b;--radius:12px;--space:24px;font-family:Arial,Helvetica,sans-serif;font-size:16px;color:var(--ink);background:var(--canvas)}
.welcome-panel{padding:38px 36px;border:1px solid var(--border);border-left:4px solid var(--accent);border-radius:var(--radius);background:white;margin-bottom:24px}.welcome-panel h2{font-size:clamp(1.9rem,3.2vw,2.8rem);font-weight:600;letter-spacing:-.035em;line-height:1.18;margin:18px 0 22px;max-width:800px}.welcome-description{font-size:1rem;line-height:1.8;color:var(--muted);max-width:710px}.welcome-actions{display:flex;align-items:center;gap:24px;flex-wrap:wrap;margin:26px 0 22px}.welcome-status{font-size:.875rem;color:var(--muted);border-top:1px solid var(--border);padding-top:18px}.welcome-status .status-dot{background:var(--accent)}.explore-paths{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:20px}.explore-path{display:flex;flex-direction:column;padding:24px;background:white;border:1px solid var(--border);border-radius:var(--radius);text-decoration:none;color:var(--ink)}.explore-path:hover{border-color:var(--accent);background:#fafdfe}.path-number{font-size:.875rem;font-weight:700;color:var(--accent);margin-bottom:22px}.explore-path h3{font-size:1.125rem;margin-bottom:10px}.explore-path p{font-size:1rem;color:var(--muted);line-height:1.7;margin-bottom:22px}.path-link{font-size:.875rem;color:var(--accent);margin-top:auto;display:flex;justify-content:space-between;gap:16px;font-weight:600}.overview-bottom{display:flex;justify-content:space-between;align-items:center;gap:20px;margin:20px 0;color:var(--muted);font-size:.875rem}.feedback-intro{display:flex;justify-content:space-between;align-items:center;gap:24px;margin-bottom:12px}.feedback-intro h2{font-size:1.4rem;margin-bottom:8px}.feedback-intro p{color:var(--muted);font-size:1rem}.feedback-privacy{font-size:.875rem;color:var(--muted);margin:12px 0 24px;max-width:800px}.feedback-list{margin-top:16px}.feedback-item{padding:22px 0;border-top:1px solid var(--border)}.feedback-item:first-child{border-top:0}.feedback-meta{display:flex;gap:12px;align-items:center;flex-wrap:wrap;color:var(--muted);font-size:.875rem;margin-bottom:10px}.feedback-meta strong{color:var(--ink)}.feedback-message{font-size:1rem;line-height:1.7;white-space:pre-wrap;overflow-wrap:anywhere}.feedback-actions{display:flex;gap:20px;margin-top:10px}.feedback-empty{padding:32px 0;text-align:center;color:var(--muted);font-size:1rem}.feedback-form label{display:grid;gap:7px;font-size:.875rem}.feedback-form input,.feedback-form select,.feedback-form textarea{width:100%}.feedback-form textarea{resize:vertical;min-height:112px;font:inherit}.feedback-form .form-grid{margin:16px 0}.feedback-form .caption{font-size:.875rem}.feedback-pin{max-width:180px}.feedback-form .hp-field{position:absolute;left:-10000px;width:1px;height:1px;overflow:hidden}.feedback-form .notice{margin-top:16px}.feedback-form .form-actions{display:flex;gap:12px;align-items:center;flex-wrap:wrap;margin-top:20px}.danger{background:#a5293b;color:white}.danger:hover{background:#852234}.feedback-quote{border-left:3px solid var(--border);padding:12px 16px;margin:16px 0;background:var(--canvas);overflow-wrap:anywhere}.feedback-form fieldset{padding:0;margin:0;border:0;min-width:0}.feedback-form .turnstile-area{margin-top:18px;min-height:0}
*{box-sizing:border-box}body{margin:0;line-height:1.5}button,input,select,textarea{font:inherit}button,a,input,select{touch-action:manipulation}button,a{ -webkit-tap-highlight-color:transparent}button{cursor:pointer}a{color:var(--accent)}button:disabled{cursor:not-allowed;opacity:.55}button:focus-visible,a:focus-visible,input:focus-visible,select:focus-visible,textarea:focus-visible,summary:focus-visible{outline:3px solid #179d9a;outline-offset:4px}h1,h2,h3,p{margin:0}h1{font-size:1.75rem;letter-spacing:-.035em;font-weight:650}h2{font-size:1.125rem;letter-spacing:-.015em}h3{font-size:1rem}small{font-size:.8125rem}[hidden]{display:none!important}.skip{position:fixed;top:-90px;left:12px;z-index:99;background:white;padding:12px}.skip:focus{top:10px}.rail{position:fixed;inset:0 auto 0 0;width:228px;background:var(--nav);color:white;padding:32px 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input{min-height:18px;width:18px;height:18px;accent-color:var(--accent)}#effectPlot{display:block;width:100%;min-width:940px;height:auto}.bar{cursor:pointer;opacity:.84}.point{cursor:crosshair;opacity:.65}.dimmed{opacity:.10}.point:focus,.bar:focus{stroke:var(--ink);stroke-width:3;outline:none}.selected-track{border-left:3px solid var(--accent);background:#f1f7f7;padding:16px;margin-top:16px}.selected-track>div{display:flex;justify-content:space-between;gap:16px}.selected-track pre{font: .875rem/1.7 Arial,sans-serif;white-space:pre-wrap;overflow-wrap:anywhere;margin-bottom:0}.workspace-footer{font-size:.8125rem;color:var(--muted);display:flex;justify-content:space-between;align-items:center;gap:16px;margin:24px 0}.notice{border:1px solid #d7bd83;background:#fffbef;border-radius:7px;padding:12px 16px;margin-bottom:18px;font-size:.875rem}.notice.error{color:#92253b;border-color:#e2b4bd;background:#fff4f6}dialog{padding:0;border:1px solid var(--border);border-radius:14px;box-shadow:0 24px 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@media(min-width:1750px){main{margin-right:auto;margin-left:calc(228px + (100vw - 1750px)/2)}}
@media(max-width:1100px){.rail{width:190px;padding:28px 12px}main{margin-left:190px;padding:28px 24px}.brand{font-size:1.3rem}.select-label{flex-direction:column;align-items:flex-start;gap:4px}.summary-row{gap:16px}.metric+.metric{padding-left:16px}.figure-card{padding:20px}.context-row{align-items:flex-start}}
@media(max-width:760px){.rail{position:relative;width:100%;padding:16px}.brand{font-size:1.35rem;display:block}.brand small{display:none}.rail nav{display:flex;gap:4px;margin-top:14px;flex-wrap:wrap}.rail nav a{flex:1;justify-content:center;padding:10px 7px;font-size:.875rem;white-space:nowrap}.rail nav a span{display:none}.rail-bottom{display:none}main{margin:0;padding:22px 16px}.page-head{align-items:flex-start;gap:12px;margin-bottom:22px;flex-wrap:wrap}h1{font-size:1.5rem}.eyebrow{font-size:.75rem}.head-actions{gap:8px}.button{padding:10px 14px}.selection-bar{padding:18px;flex-wrap:wrap}.select-label{flex-direction:row;align-items:center;flex:1;justify-content:space-between}.summary-row{padding:18px;grid-template-columns:1fr 1fr;gap:20px}.metric:nth-child(3){grid-column:1/-1;border-left:0;border-top:1px solid var(--border);padding:12px 0 0;display:flex}.metric:nth-child(3) dl{display:flex;gap:16px;align-items:center;flex-wrap:wrap}.metric:nth-child(3) dd{font-size:1.15rem}.metric:nth-child(3) small{display:none}.metric dd{font-size:1.5rem}.context-row{font-size:.8125rem;flex-wrap:wrap;gap:0}.figure-card{padding:16px}.card-head{align-items:flex-start;gap:10px}.card-head h2{font-size:1rem}.card-head>div{gap:8px}.figure-subhead{margin-left:0}.chart-toolbar{align-items:flex-start}.workspace-footer{align-items:flex-start;flex-direction:column}.dialog-content{padding:20px}.dialog-content dl{grid-template-columns:1fr}.dialog-content dd{margin-top:-8px}.selected-track>div{flex-wrap:wrap}}
@media(prefers-reduced-motion:reduce){*{scroll-behavior:auto!important}}
.mobile-help{display:none}.form-grid{display:grid;grid-template-columns:1fr 1fr;gap:16px;margin:18px 0}.form-grid label,.block-label{display:grid;gap:6px;font-size:.875rem}.form-grid input,.form-grid select{width:100%}.block-label textarea{width:100%;font: .875rem/1.6 ui-monospace,monospace;resize:vertical}.dialog-actions{display:flex;gap:24px;margin-top:18px}.export-layout{display:flex;align-items:center;gap:20px;margin-bottom:16px}.export-layout h3{margin:0 0 6px}.export-layout p{margin:0}.layout-glyph{border:1px solid #bfd0d6;border-radius:7px;min-width:100px;padding:7px;display:grid;gap:5px}.layout-glyph span{background:#edf4f5;color:#526c75;padding:12px 5px;font-size:.75rem;text-align:center}.layout-glyph span+span{padding:18px 5px;background:#e5f2ef}.file-list{display:grid;margin-top:12px;gap:4px}.file-link{display:flex;justify-content:space-between;gap:16px;text-decoration:none;padding:8px 10px;border-radius:5px;font-size:.875rem}.file-link:hover{background:var(--canvas)}.cohort-figure{display:block;width:100%;min-width:1280px;height:auto;margin:16px 0}.cohort-note{display:flex;justify-content:space-between;align-items:center;gap:24px;font-size:.875rem;color:var(--muted);margin:0 4px}.table-scroll{overflow:auto;margin-top:16px}table{border-collapse:collapse;width:100%;text-align:left;font-size:.875rem}th{font-weight:600;color:var(--muted);background:#f5f8f9;border-block:1px solid var(--border);padding:12px 14px;white-space:nowrap}td{border-bottom:1px solid #e7edf0;padding:12px 14px;vertical-align:top;font-variant-numeric:tabular-nums}td .text-button{padding:0}tbody tr:hover{background:#f7fafb}.table-controls{display:flex;justify-content:space-between;align-items:center;gap:16px}.table-controls label{display:flex;align-items:center;gap:12px;font-size:.875rem}.library-intro{margin-bottom:24px}.library-intro h2{font-size:1.35rem;margin-bottom:6px}.scope-strip{display:grid;grid-template-columns:repeat(4,1fr);margin-bottom:24px;gap:18px}.scope-strip>div{border-left:2px solid #9fc9c6;padding-left:14px}.scope-strip>div:nth-child(n+3){border-color:#cad7dd}.scope-strip strong{display:block;font-size:.875rem;font-weight:600}.scope-strip span{font-size:.8125rem;color:var(--muted)}.library-controls{display:grid;grid-template-columns:1.5fr 1fr;gap:20px}.library-controls label{display:grid;gap:7px;font-size:.875rem}.library-controls input,.library-controls select{width:100%}.track-name{font-weight:600}.track-assay{display:block;color:var(--muted);font-size:.75rem;max-width:350px;margin-top:4px}.pagination{display:flex;align-items:center;justify-content:space-between;gap:16px;margin-top:20px}.empty-cell{text-align:center;padding:36px}.segmented{display:flex;gap:8px;margin-bottom:20px}.segmented [aria-pressed=true]{border-color:var(--accent);color:var(--accent);background:#eaf5f3}.curve-image{min-width:940px}#effectPlot text{font-size:17px}.workspace-footer>div{display:flex;gap:20px}
@media(max-width:1000px){.scope-strip{grid-template-columns:1fr 1fr}}
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.brand small{font-size:.8125rem;line-height:1.5;overflow-wrap:normal}.feedback-filter-row{display:flex;align-items:center;gap:20px;justify-content:space-between;margin-top:16px;flex-wrap:wrap}.feedback-filter-row label{display:flex;align-items:center;gap:10px;font-size:.875rem}.feedback-filter-row select{max-width:240px}
@media(max-width:1100px){.explore-paths{gap:14px}.explore-path{padding:20px}.welcome-panel{padding:30px}.wide-break{display:none}.rail nav{margin-top:30px}}
@media(max-width:760px){.brand small{display:block;font-size:.8125rem}.rail nav a{flex:0 1 auto;min-height:44px;padding:10px}.welcome-panel{padding:24px 20px}.welcome-panel h2{font-size:2rem}.explore-paths{grid-template-columns:1fr}.path-number{margin-bottom:12px}.welcome-actions{gap:14px}.overview-bottom,.feedback-intro{align-items:flex-start;flex-direction:column;gap:12px}.welcome-status{line-height:1.7}.feedback-filter-row{align-items:flex-start}.feedback-form .form-grid{grid-template-columns:1fr}.feedback-form .form-actions{align-items:stretch}.feedback-form .form-actions .button{flex:1}.workspace-footer{overflow-wrap:anywhere}}